“Responding to the Microbial Basis
of Cardiovascular Disease”
Roberta A. Gottlieb, M.D.
Director, Donald P. Shiley BioScience Center
Frederick G. Henry Chair in Life Sciences
From The Director's Desk
March 06, 2012
Donald P. Shiley BioScience Center Dedication
On March 6, 2012, we celebrated Dalene Shiley's visionary gift, naming the Donald P. Shiley BioScience Center in honor of her late husband. Donald Shiley was an inventor and innovator whose philanthropic investments in arts and education have enriched many lives. MORE
Apr 11, 2011
$5M Shiley Gift Renames BioScience Center
“Because the BioScience Center project was of great personal and professional importance to them, it seemed appropriate to give Stephen and Susan a significant going-away present in tribute to his masterful presidency..." MORE
Jan 03, 2011
Immunoantibiotics: Vaccine Platform Holds Great Promise
A consortium has been established to explore the development of a new and novel approach for the development of vaccines in both young and aged individuals. MORE
October 14, 2010
Grant Funds BioScience Center's New Research Tool
A new imaging system will help track the spread of disease and damage after a heart attack. MORE
August 02, 2010
In Memoriam: Donald Shiley
We are deeply saddened at the news of Donald Shiley’s passing. Donald was a humanitarian in the truest sense. His contributions, both as an inventor and philanthropist, will leave a lasting legacy in our community and beyond... MORE
March 10, 2010
BSC UpData March 2010
Researchers in the BioScience Center have been thinking about autophagy. Autophagy (literally "self-eating") is a process where cells recycle bits and pieces of themselves through a pathway involving an autophagosome... MORE
February 01, 2010
Go Red for Women
February 5th is the day to wear red in support of the American Heart Association's "Go Red for Women" Campaign... MORE
December 15, 2009
BSC Feature December 2009
The Domino Effect: Surprising Links Between Infection and Heart Disease. MORE
November 10, 2009
BSC UpData November 2009
The entrepreneurial side of the BioScience Center is emerging. My vision for the BSC is to improve health through strategies of basic research, public health measures, and commercial development. MORE
October 30, 2009
Vaccination Fascination
SDSU research professor Ed Morgan discusses vaccinations, their scarcity and why they are important. MORE
October 29, 2009
BSC Feature October 2009
'Neglected Infections' Resurface Among America's Poor... MORE
September 16, 2009
BSC UpData September 2009
The SDSU BioScience Center continues to advance its mission to study the critical nexus of infection, inflammation, and cardiovascular disease. I hope you had a delightful summer... MORE
July 01, 2009
BSC UpData July 2009
Five world-renowned immunologists moved into the Donald P. Shiley Cardiovascular Research Center. All of their research, including projects on T cells, microRNA and vaccine development, intersects in some way with heart disease... MORE
June 01, 2009
BSC UpData June 2009
Construction is scheduled to be complete by June 15. Invitations have been sent out for the celebration of the Donald P. Shiley Cardiovascular Research Center which will take place on July 15. We hope it will be a memorable occasion. MORE
May 01, 2009
BSC UpData May 2009
With the imminent completion of the BSC's third floor, we have made a significant advance toward assembling the full team of collaborative investigators. MORE
February 11, 2008
A Gift from the Heart
Darlene Shiley is giving new meaning to a gift from the heart by donating $1.25 million in her husband's name to San Diego State University for heart disease research. MORE
February 01, 2008
BioScience Center Assembles Team of Investigators
The BioScience Center has assembled a team of investigators to explore the link between gum and heart diseases. MORE
January 08, 2008
Risky Receptor Regulators
Members of the Gottlieb Lab and collaborators from Scripps Research Institute published a paper reporting potentially dangerous effects of a drug that binds to a specific receptor for the bioactive lipid sphingosine-1phosphate (S-1-P). MORE
January 01, 2008
SDSU BioScience Center to Study Link Between Periodontitis and Atherosclerosis
The SDSU BioScience Center was established to study the links... MORE
January 01, 2008
Taking a Peek at Intracellular Housekeeping
Cells use a process called autophagy (literally, eating oneself) to survive periods of starvation and to clean up damaged organelles... MORE
December 30, 2007
SDSU BioScience Center to Study Link Between Periodontitis and Atherosclerotic Heart Disease
Atherosclerosis, or hardening of the arteries, is responsible for coronary artery disease, stroke, and peripheral vascular disease... MORE
December 13, 2007
Frontiers in Mitochondrial Research
Dr. Gottlieb and Dr. Frey presented work at the Frontiers in Mitochondrial Research meeting held in Italy November 25-29. MORE
November 23, 2007
SDSU BioScience Center Investigators in Action at the American Heart Association
At the recent American Heart Association meeting held in Orlando FL, in November 4-7, 2007, BioScience Center investigators presented their latest... MORE
July 20, 2007
Symposium Explored Links Between Heart Disease and Viruses
"This event was a great opportunity to explore this new area of study in heart disease," said Stanley Maloy, dean of the College of Sciences and former president of the American Society for Microbiology. MORE
March 06, 2012
Donald P. Shiley BioScience Center Dedication
By Sandy Liarakos and Roberta Gottlieb
Visionaries Donald and Darlene Shiley
On March 6, 2012, we celebrated Dalene Shiley's visionary gift, naming the Donald P. Shiley BioScience Center in honor of her late husband. Donald Shiley was an inventor and innovator whose philanthropic investments in arts and education have enriched many lives. he event was attended by friends of San Diego State University and supporters of the Shiley BioScience Center, including luminaries Dr. Darlene Shiley (Hon.) and Mayor Jerry Sanders.
"Because of Donald and Darlene's generous gift to the Center, bioscience research is accelerating research on the role of infection and inflammation in causing chronic diseases like heart disease. It is their commitment and dedication to solving medical problems with innovation and collaborative-based research that inspire our work, and will make a difference for decades to come." said Stanley Maloy, Ph.D., Dean of the College of Sciences.
President Elliot Hirshman, Ph.D., who joined SDSU in July 2011, also spoke at the dedication."I am thrilled this facility bears the name of Donald P. Shiley, whose extraordinary contributions to the biomedical field will be represented here at San Diego State. I can think of no better way to honor his legacy than his name on this building."
The Donald P. Shiley BioScience Center is an innovative San Diego State University research facility with the mission to understand how chronic infections contribute to cardiovascular disease and other chronic, age-related diseases. In the five years since it opened, scientists in the center have published over 100 articles, filed 5 patents, and garnered nearly $14 million in NIH funding for their research.
Newly Named Entrance
"Completion of the second floor will allow us to translate the important discoveries being made at SDSU into diagnostics and therapeutics that can benefit patients," said Roberta Gottlieb, M.D., director of the Donald P. Shiley BioScience Center.The space is designed to support innovators carrying out proof-of-concept work necessary to move basic science insights from the laboratory bench to the patient's bedside.By facilitating interdisciplinary collaboration between biotechnology entrepreneurs and basic scientists, Gottlieb hopes to accelerate the successful development of new technology.