Transcriptional Repressors

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Transcriptional repressors are proteins that bind to specific sites on DNA and prevent transcription of nearby genes. (RNA can also inhibit transcription, but inhibitory RNAs are not usually called repressors.)

Most repressors inhibit the initiation of transcription. The following cartoons give a simple overview of the inititation of transcription, and show three ways that repressors can inhibit transcription.

A brief overview of the lac operon can be found in the MIT online textbook.

SOME USEFUL GENERAL REVIEWS ON REPRESSORS:


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Last modified July 29, 2004