Dr. Dinsdale’s lab at San Diego State University uses next-generation sequencing to tease apart ecological and evolutionary relationships within marine, coral reef and kelp forest ecosystems. We are a multi-disciplinary team of students and researchers from around the globe. Dr. Dinsdale helped establish one of the first university-level classes to offer hands-on experience with a pyrosequencing machine. In 2011, students of BIOL596 Ecological Metagenomics at SDSU sequenced the California sea lion genome at 12X coverage. Students applied bioinformatics and statistics techniques to analyze the resulting genomes and metagenomes.
We apply DNA sequencing technology to answer questions in microbial ecology and genetics.
Silveira C. B., F. H. Coutinho, G. Cavalcanti, A. C. Soares, G. G. Z. Silva, V. A. Cantu, M. Doane, B. Knowles, R. B. Francini-Filho, C. C. Thompson, E.A. Dinsdale, G. B. Gregoracci, F. Rohwer, F. Thompson. 2017. Bacteriophage genomic signatures and transfer of bacterial virulence genes in coral reefs. Frontiers in Microbiology 8:784 Silveira, C. B., G. S. Cavalcanti, J. Walter, A. W. Silva-Lima, E.A. Dinsdale, D. Bourne, C. C. Thompson, F. L. Thompson. 2017. Microbial processes driving coral reef organic carbon flow. FEMS Microbiology Reviews doi: 10.1093/femsre/fux018 Andrade, A. C. A. Fróes, F. Álvares Cardoso Lopes, F. L Thompson, R. Henrique Krüger, E. Dinsdale, T. Bruce. 2017. Diversity of microbial Carbohydrate-Active enZYmes (CAZYmes) associated with freshwater and soil samples from Caatinga Biome. Microbial Ecology 1-17 Walsh, K, J.M. Haggerty, J. Spangler, M.B. Turner, C. Lee, G. Amado-Filho, R. Francini-Filho, C.B. Silveira, R. L. Moura, TT. Harkins, R. A. Edwards, F.L. Thompson, and E. A. Dinsdale. 2017. Aura-biomes are present in the water layer above coral reef benthic macro-organisms. Peer J DOI 10.7717/peerj.3666 Doane, M.P. J. M. Haggerty, D. Kacev, B. Papudeshi, E. A. Dinsdale. 2017. The skin microbiome of the Common thresher shark (Alopias vulpinus) has low taxonomic and gene functional β-diversity. Environmental Microbiology Reports Morris Megan M., Haggerty John M., Papudeshi Bhavya N., Vega Alejandro A., Edwards Matthew S., Dinsdale Elizabeth A. 2016. Nearshore Pelagic Microbial Community Abundance Affects Recruitment Success of Giant Kelp, Macrocystis pyrifera. Frontiers in Microbiology. doi: 10.3389/fmicb.2016.01800 Haggerty, J. M. and E. A. Dinsdale. 2016. Distinct Biogeography and Evolution of Marine Microbial Taxonomy and Function. Journal of Global Ecology and Biogeography. DOI: 10.1111/geb.12528 Haas, A.F., M F. M. Fairoz, L W. Kelly, C E. Nelson, E. A. Dinsdale, R. A. Edwards, S. Giles, M. Hatay, N. Hisakawa, B. Knowles, Y. W. Lim, H. Maughan, O. Pantos, T. Roach, S. E. Sanchez, C. B. Silveira, S. Sandin, J. E. Smith, and F. Rohwer. 2016. Global microbialization of coral reefs. Nature Microbiology doi:10.1038/nmicrobiol.2016.42 Knowles B, Silveira CB, Bailey BA, Barott K, Cantu A, Cobián-Güemes AG, Coutinho FH,Dinsdale E, Felts B, Furby KA, George EE, Green KT, Gregoracci GB, Haas AF, Haggerty JM, Hester ER, Hisakawa NG, Kelly LW, Lim YW, Little M, Luque A, McDole-Somera T, McNair K, de Oliveira LS5, Quistad SD, Robinett NL, Sala E, Salamon P, Sanchez SE, Sandin S, Silva GGZ, Smith J, Sullivan C, Thompson C, Vermeij MJA, Youle M, Young C, Zgliczynski B, Brainard R, Edwards RA, Nulton J, Thompson F, Rohwer F. Lytic to Temperate Switching of Viral Communities. Nature. 531: 466-470 Haas, A.F., M. Guibert, A. Foerschner, T. Co, S. Calhoun, E. George, M. Hatay, E.A. Dinsdale, S. Sandin, J.E. Smith, M. Vermeij, B. Felts, P Dustan, P Salamon and F Rohwer. 2015. Computational evaluation of coral reef aesthetics. Peer J DOI 10.7717/peerj.1390